How Does cheap cialis Work
An erection occurs when blood is pumped to the penis which makes it hard allowing sexual intercourse. This action is impossible in some men because they experience penile dysfunction. More and more men in recent years have been admitting that this is a problem for them and asking for help. In Bothell Washington, a small company began research and subsequent development of a drug called cheap cialis to help men with their problem.
There are a group of drugs called PDE5 enzyme inhibitors and Cialis fits in to this. It was discovered by researchers that cyclic guanosine monophosphate (cGMP) was the key to achieving and sustaining an erection. Following sexual stimulation a chain reaction occurs in the tissue of the penis of a man that results in elevated levels of cGMP. With sufficient levels of cGMP, the penis can remain erect and the more cGMP the more robust is the erection.
Cialis works by blocking the enzyme PDE5 which is responsible for neutralization of cGMP. Because Cialis is very highly selective inhibitor of PDE5 it is very effective. Cialis on its own does not cause an erection, Cialis blocks the degradation of cGMP produced in reaction to sexual stimulation. It is important to understand that if you are not being sexually stimulated there is no cGMP to protect so Cialis remains in the background. This is why Cialis is so different from some other medications for the problem. There were many drugs for penile dysfunction before Cialis, which induced a chemical reaction instead of one which reacted to stimulation. It was found that this was one of the main complaints by couples who were taking other types of drugs and did not seem to be natural.
By blocking the enzyme PDE5 Cialis effectively causes the blood vessels in the penis to relax and allowing the blood to flow and enlarge this. By compressing the veins at the base of the penis the flow of blood from this is restricted and the erection is maintained. Following intercourse these veins relax allowing the blood to flow out as normal. Correctly used Cialis, means that sexual activity is as natural as not having to use it at all.Because Cialis is easily absorbed into the bloodstream it can be taken from 30 minutes up to 12 hours prior to sexual activity and Cialis is active for between 24 and 36 hours. According to the manufactures, because of its unique onset and duration periods, Cialis can be taken many hours before sexual activity is contemplated.
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